Locations

Tel Aviv, Israel

Email Us

capsibreed@gmail.com

CapsiBreed - Investment

Transforming Pepper Breeding Through Molecular Innovation
About The Company

CapsiBreed

Developed at The Hebrew University of Jerusalem—Israel’s top-ranked research institution and a global leader in plant sciences—CapsiBreed is the commercial realization of over a decade of groundbreaking academic work led by Prof. Alexander Vainstein, a pioneer in plant genetic engineering and molecular biology. Prof. Vainstein’s lab at HUJI has been at the forefront of metabolic engineering, plant transformation, and advanced genome editing technologies.

CapsiBreed is a Tel Aviv–based ag-biotech company pioneering gene editing in peppers through its proprietary platform, PepGEM™. Built on years of academic research and scientific refinement, PepGEM™ enables precise, rapid, and efficient modification of hot and sweet pepper varieties—overcoming the longstanding biological barriers of pepper transformation. The platform empowers seed companies to introduce high-value traits such as improved shelf life, flavor, yield, nutrition, and disease resistance in a fraction of the time and cost required by traditional breeding. By offering both trait development and molecular breeding services, CapsiBreed is shaping the future of functional food ingredients and sustainable agriculture.

Hebrew University of Jerusalem

Prof. Alexander Vainstein

Peppers (Capsicum annuum)

Peppers
Peppers
Peppers
Peppers

Dr. Oded Skaliter: Engineering Healthier Crops Through Science and Vision

Dr. Oded Skaliter’s passion for plant science was first sparked by his grandfather, an international expert in desert agriculture. As an undergraduate, he was introduced to groundbreaking research on anthocyanin-rich purple tomatoes developed in the laboratory of Prof. Cathie Martin—a moment that shaped his future direction. He became intrigued by the possibilities molecular biology offered for improving crops for human health and knew this was the path he would pursue professionally.

Today, as the co-founder of CapsiBreed, Dr. Skaliter is helping the agriculture and food industries develop crops enriched with natural health-promoting compounds. With a PhD in Plant Sciences from the Hebrew University of Jerusalem, he combines strong academic expertise with an entrepreneurial mindset focused on real-world value.

Pepper Gene Editing and Modification

Exclusive license for PepGEM™

CapsiBreed holds an exclusive license for PepGEM™ (Pepper Gene Editing and Modification), a proprietary gene-modification platform developed by Prof. Alexander Vainstein at The Hebrew University of Jerusalem (HUJI). PepGEM™ is designed to overcome the biological recalcitrance of hot and sweet peppers—a longstanding barrier in the application of advanced molecular breeding tools to this economically important crop.
A Global Leader in Innovation and Agricultural Science

The Hebrew University of Jerusalem

Founded in 1918, The Hebrew University of Jerusalem (HUJI) is one of the world’s most respected academic institutions and Israel’s leading center for scientific research, technology development, and entrepreneurship. Consistently ranked among the top 100 universities globally and recognized as Israel’s most productive research university, HUJI has been the origin of countless groundbreaking discoveries that have shaped industries ranging from medicine and cybersecurity to agriculture and biotechnology.

With over 100 years of academic excellence, the university is home to eight Nobel Prize laureates, numerous Fields Medal and Israel Prize winners, and hundreds of patents and technologies that have led to the creation of market-defining companies.

 

Hebrew university of Jerusalem

The Robert H. Smith Faculty of Agriculture, Food and Environment, based in Rehovot, is particularly renowned for its expertise in plant sciences, genomics, molecular biology, and agritech innovation. It is here that the scientific foundation of CapsiBreed was developed, through more than a decade of research into genetic transformation, precision breeding, and advanced tissue culture in peppers, led by world-renowned experts, including Prof. Alexander Vainstein.

HUJI’s technology transfer company, Yissum, has facilitated the commercialization of thousands of innovations and the launch of over 200 successful startups. Companies like Mobileye (acquired by Intel for $15.3 billion), BriefCam (acquired by Canon), and OrCam (AI-based vision technology) all trace their origins back to research conducted at the Hebrew University.

This deep-rooted culture of excellence and impact has made HUJI a trusted partner of global industry leaders, governments, and research institutions. Its dedication to applied science and translational research makes it a catalyst for innovation with global reach—and CapsiBreed is proud to continue that legacy by bringing next-generation gene editing technology to the agricultural market.

Benefits

The benefits of CapsiBreed’s gene-edited pepper seeds across different industry sectors

highlighting how tailored traits bring specific value to agriculture, food, health, and commercial markets:

Agriculture & Farming

  • Higher Yields → More produce per hectare, increasing profitability for growers
  • Disease Resistance → Reduced crop loss and lower dependency on chemical pesticides
  • Shelf Life Extension → Easier logistics, less post-harvest waste, higher ROI
  • Climate Resilience → Tolerance to heat, drought, or variable growing conditions

Agriculture & Farming

Food Industry

Food Industry

  • Enhanced Flavor Profiles → Customized sweetness, heat, or aroma to suit global tastes
  • Consistent Quality → Uniform appearance, texture, and ripening across harvests
  • Reduced Spoilage → Less shrinkage in retail and food service supply chains
  • Novel Varieties → Market differentiation for premium or specialty peppers

Health & Nutrition

  • Increased Capsinoids & Carotenoids → Natural compounds known for anti-inflammatory, antioxidant, and metabolic benefits
  • Functional Foods → Foundation for wellness-oriented products (e.g., fortified sauces, supplements)
  • Clean-Label Ingredients → GMO-free gene-edited crops with no foreign DNA

Health & Nutrition

AgTech Firms

Seed Companies & AgTech Firms

  • Faster Breeding Cycles → 3× faster time-to-market vs. traditional methods
  • Trait Licensing Opportunities → Competitive differentiation and new revenue streams
  • Custom Trait Development → Contract services to edit elite germplasm
  • Stacked Traits → Combine multiple improvements in one genetic line (e.g., flavor + disease resistance)

Pharmaceutical & Nutraceutical Markets

  • Plant-Based Actives → Biofortified peppers as sources of specific health compounds
  • Controlled Metabolite Expression → Reliable raw material for supplement production
  • Platform for Biomanufacturing → Future potential for metabolite synthesis in peppers

Pharmaceutical

Peppers
Our Technology Impact

Efficiency & Performance

Faster Breeding Cycle

300% faster breeding cycle compared to conventional methods

Reduced Trait Development Time

Trait development time reduced from 5–7 years → 1–2 years

Transformation Efficiency

Up to 5x higher success rates in pepper editing (vs. traditional transformation protocols)

Multiplex Gene Editing

Supports 3+ traits in a single modification cycle

No Off-Target Edits

Validated with PCR, sequencing, and AI-based guide RNA design

Peppers Breeding Challenges

CapsiBreed's Technology Solution

Limited to existing gene pool

Only traits that already exist in sexually compatible plants may be introduced

Costly

Developing a new variety typically costs $2-3 million USD

Time-consuming

A new variety can take 7–15 years and requires many generations of crossing and selection

Laborious

Requires manual selection, crossbreeding & multiple generations to achieve the desired traits

Imprecise

Introduces many unknown or undesired traits along with the target ones
a red pepper with a dna strand inside

Beyond the boundaries of natural variation

Novel traits may be introduced or created beyond what exists in nature

Economical

Less than $1 million USD for development of new varieties

Fast

1-2 years for development of new varieties

Labor-efficient

No need for large scale crossing and growing numerous offsprings

Precise

Avoids introduction of undesirable genes
Why Choose Us

Our technology delivers exceptional results.

Organic Foods Provides
Organic Foods Provides
Organic Foods Provides
Why Peppers?

The Pepper Global Market

Capsicum annuum

Global Popularity and High Demand

Peppers are a $100B global crop with fast-growing demand.

High economic value

They offer high margins and multi-billion-dollar market potential.

Nutritious & healthy

Peppers are rich in vitamins, antioxidants, and health compounds.

Versatile market use

Used in food, health, cosmetics, and functional products.

Broad Agronomic Adaptability

Peppers grow in diverse climates around the world.

Unmet Innovation Potential

Modern breeding tools are just beginning to reach peppers.

CapsiBreed Advantages

CapsiBreed combines cutting-edge gene editing with deep crop expertise to overcome the toughest barriers in pepper breeding. Our proprietary PepGEM™ technology enables faster, more precise development of high-value traits—delivering novel pepper varieties that meet the needs of seed companies, growers, and consumers. With validated results, strategic partnerships, and a first-mover edge, CapsiBreed is redefining what’s possible in hot and sweet pepper innovation.

Revenue Streams

CapsiBreed's Market Potential

Service fees

High-value gene editing services priced per project (~$150-500K)

Royalities

Earn 5% royalties when clients use our edited traits in commercial products

Technology Sublicensing

Earn ongoing royalties from trait development and tech use

Blue Sky Projects

Pursue visionary R&D with breakthrough commercial potential
red-pepper-isolated-on-white-background-2024-10-22-21-37-40-utc copy

$701 Million
Pepper Seeds Market

$3.5 BillionPlant Genome Editing and
Genetic Engineering Market

Patents

Secure exclusive rights to new, high-performing pepper varieties

Sales of Seeds

Sell elite, gene-edited pepper seeds directly to global markets.

Monthly / Yearly Fees

We charge sublicensing fees for the use of our gene-targeting technology

PROJECT COST ANALYSIS

Cost of a $100K For a new pepper trait
  • Faster Breeding Cycles → 3× faster time-to-market vs. traditional methods
  • Trait Licensing Opportunities → Competitive differentiation and new revenue streams
  • Custom Trait Development → Contract services to edit elite germplasm
  • Stacked Traits → Combine multiple improvements in one genetic line (e.g., flavor + disease resistance)

Our Global Partners

Partnership with BreedX

CapsiBreed is now in a strategic partnership with BreedX, a well-established Israeli ag‑biotech innovator known for its consumer‑focused seedless Sweet Seedless Pepper (SLP) “Pepperito®” and taste-driven tomato varieties. BreedX’s premium genetics and global commercialization experience complement CapsiBreed’s gene-editing innovation, enabling a powerful joint value proposition based on rapid trait commercialization and differentiated product launches.​

Contract with Erma Zaden

CapsiBreed partnered with Dutch seed company Erma Zaden to develop gene-edited pepper varieties using PepGEM™. The agreement provides access to elite germplasm, shared IP rights on new traits, and future royalties from commercial sales. It also expands CapsiBreed’s market reach to Europe, Morocco, Mexico, and the U.S. while strengthening its position in the global pepper seed market.

Regulatory Partnership for U.S. Market Entry

CapsiBreed has signed a Letter of Intent with a U.S.-based agricultural biotech company to support regulatory approval for its gene-edited pepper varieties. This collaboration brings critical expertise in navigating the USDA’s approval process, accelerating CapsiBreed’s path to commercialization in the United States and Australia. The partnership enhances CapsiBreed’s regulatory readiness while reinforcing its position as a global leader in precision pepper breeding.

“Tnufa” Grant – Israel Innovation Authority

CapsiBreed was awarded a Tnufa grant from the Israel Innovation Authority to support the development of proof-of-concept pepper lines with resistance to TSWV (Tomato Spotted Wilt Virus) and Western flower thrips—two major global threats to pepper production. The grant recognizes the innovation and commercial potential of CapsiBreed’s PepGEM™ platform, and strengthens its eligibility for future funding programs, including the Pre-Seed matching grant of up to $300,000. This support affirms CapsiBreed’s leadership in trait-driven crop innovation.

AgTech Investment

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Location

Tel Aviv, Israel

Email Address

capsibreed@gmail.com

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